EFFECTS OF NUTRITIONAL TREATMENT ON THE QUALITY OF LIFE IN THE PATIENTS AFTER RADICAL SURGERY FOR COLON CANCER
Bekisheva A., Makishev A.
Astana Medical University, Nur-Sultan, Kazakhstan
Malnutrition is one of the complications following surgical resection of the colon. Aim - to study the impact of enteral nutritional supplements and high-calorie diet on to nutritional status and quality of life within 12 months after surgical treatment.
220 patients after surgery of the colon cancer are divided into 3 groups: group 1 (G1 n=68) - enteral nutrition, group 2 (G2 n=64) - high-calorie diet, group 3 (G3 n=88) - patients with baseline high PNI, follow-up. Nutritional status, NRS-2002 and EORTC QLQ C 30 questionnaire were analyzed.
In G1 there was an increase in body weight, BMI and improvement of laboratory parameters compared with G2, where body weight, BMI and laboratory parameters remained unchanged (p<0.03). In G3 there was a decrease in body weight, BMI and a deterioration in blood counts (p>0.06). In G1, functional indicators of quality of life were improved (p<0.002), which had a positive correlation with nutrition indicators (p<0.05). In G2, an improvement in 3 functional scales (p<0.003), but not as significant as in G1. In G3 deterioration of all functional and symptomatic scales that had a close correlation with malnutrition (p<0.05).
Special enteral nutrition had a more positive effect on the nutritional status and quality of life than a high-calorie diet. Also, despite the initial high PNI and the lack of malnutrition in the preoperative period, the majority of patients 1 year after surgery are subject to the development of malnutrition.
Quality of Life
Republic of Kazakhstan