EVALUATING ORAL AND MAXILLOFACIAL HEALTH CHALLENGES IN INTRAVENOUS DRUG USERS: A CROSS-SECTIONAL STUDY OF DRUG REPLACEMENT THERAPY PARTICIPANTS AND NON-PARTICIPANTS 
Nino Chichua, Giuli Margishvili, Grigol Dzodzuashvili, Rusudan Ivanishvili, Vladimer Margvelashvili.
Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Center for Mental Health and Prevention of Addiction, Tbilisi, Georgia.
University of Georgia, Tbilisi, Georgia.
6-13

PECULIARITIES OF THE SECOND MESIOBUCCAL CANAL IN MAXILLARY FIRST MOLAR: A RETROSPECTIVE ANALYSIS
Fomenko Yu.V, Sukhostavets E, Hrechko N.B, Kuzina V.V, Mikhailenko N.M, Yaroslavska Yu.Yu, Skliar S.O, Mikulinska-Rudich Yu.M, Vlasov A.V, Smorodskyi V.O, Nazaryan R.S.
Kharkiv National Medical University, Kharkiv, Ukraine.
14-20

EFFECTIVENESS OF COMBINED SURGICAL AND HORMONAL THERAPY IN TREATMENT OF ENDOMETRIOMAS
Chikhashvili E, Kristesashvili J, Urjumelashvili M.
MD, Phd. Student, Iv. Javakhishvili Tbilisi State University, Faculty of Medicine, Department of Clinical and Research Skills, Tbilisi, Georgia.
Associated Professor of Iv. Javakhishvili Tbilisi State University, Faculty of Medicine, Department of Obstetrics – Gynecology – Reproductology, Tbilisi, Georgia.
MD PHD, Assistant Professor, The Faculty of Medicine at University Geomedi, Georgia.
21-29

ACUTE FORMS OF CORONARY ARTERY DISEASE IN THE NOSOLOGICAL STRUCTURE OF HOSPITALIZATION OF YOUNG PEOPLE IN ALMATY CITY CARDIOLOGY CENTER
Lazzat I. Zhussupbekova, Dinara A. Nurkina, Saule М. Sarkulova, Galiya T. Smailova, Kassymzhomart N. Zholamanov.
Department of Internal Medicine with a course of nephrology, haematology, allergology and immunology, Astana Medical University, Astana 010000, Kazakhstan
Department of Cardiology, Astana Medical University, Astana 010000, Kazakhstan
Astana Medical University, Astana 010000, Kazakhstan.
30-36

NOCTURNAL ENURESIS SYMPTOMS AND RISK FACTORS AMONG CHILDREN AND ADOLESCENTS IN QASSIM REGION, SAUDI ARABIA
Alwashmi Emad, Alharbi Adel H, Almadi Abdulaziz S, Alhuraysi Abdulaziz, Almuhanna Mousa M, Alharbi Badr.
Department of Surgery, College of Medicine, Qassim University, Buraydah, Saudi Arabia.
37-44

STATE OF INPATIENT MEDICAL CARE PATIENTS WITH ACUTE PANCREATITIS
Askar Zh. Akhmetov, Tolkyn A. Bulegenov, Meirbek Zh. Aimagambetov, Nazarbek B. Omarov, Altay A. Dyusupov, Assel Zh. Baybussinova, Aldiyar E. Masalov, Samatbek T. Abdrakhmanov, Medet Ә. Ayenov.
Department of Hospital Surgery, Anesthesiology and Reanimatology NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
Chairman of the Board Rector NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
Department of Epidemiology and Biostatistics NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
45-51

DETECTION OF MECA AND NUC GENES OF MULTI-DRUG RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM DIFFERENT CLINICAL SAMPLES
Saad H . Abood, Liwaa A. Shihab, Ghufran H. Abed, Thanon Y. Azzawi, Ahmed S. Abood.
College of Education, Al-Iraqia University, Baghdad, Iraq.
College of Health Medical Techniques, Al-Bayan University, Baghdad, Iraq.
52-54

THE EFFECT OF INTRANASAL ADMINISTRATION OF BIOLOGICALLY ACTIVE SUBSTANCES OF AMINO ACID AND PEPTIDE NATURE ON THE MONOAMINE SYSTEMS OF THE BRAIN
Sergey A. Apryatin, Vyacheslav I. Moiseenko, Raul R. Gainetdinov, Vera A. Apryatina.
Institute of Translational Biomedicine, Saint Petersburg State University, 199034 Saint Petersburg, Russia
55-67

DERMATOFIBROSARCOMA PROTUBERANS: WIDE LOCAL EXCISION AS DERMATOSURGICAL APPROACH WITH FAVOURABLE FINAL OUTCOME-CASE PRESENTATION AND SHORT UPDATE ON THERAPEUTIC OPTIONS
Tchernev G, Broshtilova V, Kordeva S.
Onkoderma- Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606 Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Institute of Ministry of Interior, General Skobelev 79, 1606, Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Military Academy, Sofia, Bulgaria.
68-71

DEVELOPMENT OF ENDOSALPINGIOSIS IN PATIENTS WITH A HISTORY OF BREAST CANCER
Yuuka Matsumoto, Takuma Hayashi, Yasuaki Amano, Kaoru Abiko, Ikuo Konishi.
Department of Obstetrics and Gynecology, National Hospital Organization Kyoto Medical Center, Kyoto city, Kyoto, Japan.
Cancer Medicine, National Hospital Organization Kyoto Medical Center, Kyoto city, Kyoto, Japan.
Seeds Development and Research Platform Project, Japan Agency for Medical Research and Development (AMED), Chiyoda-ku, Tokyo, Japan.
Kyoto University Graduate School of Medicine, Kyoto city, Kyoto, Japan.
72-76

POSSIBILITY OF IMPROVING DISEASE PREDICTION USING MATHEMATICAL MODELS
Ilenko-Lobach N.V, Boychenko O.M, IlenkoN.M, Salomatina S.O, Nikolishyna E.V, Karnauh M.M, Voloshyna A.V, Zaitsev A.V.
Associate Professor of the Department of Therapeutic Stomatology, Poltava State Medical University, Poltava, Ukraine.
Associate Professor of the Department of Therapeutic Stomatology, Dnipro State Medical University, Ukraine.
Associate Professor of the Department of Therapeutic Stomatology, Zaporizhia State Medical and Pharmaceutical University, Ukraine.
77-79

PROSPECTS AND LONG-TERM RESULTS AFTER ENDODONTIC SURGERY
Khabadze Z.S, Mer I.Ya, Fokina S.A, Mityushkina T.A, Kakabadze E.M, Badalov F.V, Dolzhikov N.A, Saeidyan S, Umarov A.Yu, Wehbe A.
Department of Operative Dentistry, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Institute of Medicine, Miklukho-Maklaya str. 6, Moscow 117198, Russia.
80-86

NEVI IN CHILDREN: CLINICO-DERMOSCOPIC CONCEPTS ASSOCIATED WITH LOCATION
Khatuna Kudava.
European University, department of dermatology, Tbilisi, Georgia.
87-90

BREAST CANCER AND DIAGNOSTIC METHODS: UNDERSTANDING THE ROLE OF BRCA1 AND BRCA2
Jonathan Borges, Rashmi Aithmia, Jahnvi Mittal, Tarang Bhatnagar, Shivangi Gupta, Bhavuk Samrat.
Senior Tutor, Department of Medical-Surgical Nursing, KAHER Institute of Nursing Sciences, Belagavi, India.
MD, DCP, DNB, MNAMS, DipRCpath, Department of Pathology, GMCH Jammu, Jammu and Kashmir, India.
Mbbs 4th Year Student, Department of medical, Jss Medical College Mysore, India.
Centre of Research Impact and Outcome, Chitkara University, Rajpura- 140417, Punjab, India.
Quantum University Research Center, Quantum University, India.
Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh-174103, India.
91-98

GENETIC VARIANTS IN ANTIPSYCHOTIC METABOLISM: POLYMORPHISM PROFILES IN KAZAKH COHORT WITH PARANOID SCHIZOPHRENIA
Kovaleva Kristina, Zulfiya Kachiyeva, Aigulim Abetova, Natalia Raspopova.
S.D. Asfendiyarov Kazakh National Medical University; Kazakhstan, 050000 Almaty, Tole bi st., 94.
Republican Scientific and Practical Center of Mental Health, Almaty, Kazakhstan.
Kazakh Russian Medical University Almaty, Kazakhstan.
99-103

PERCUTANEOUS OCCLUSION OF MAJOR AORTOPULMONARY COLLATERALS IN TRANSPOSITION OF THE GREAT ARTERIES USING AMPLATZER PICCOLO OCCLUDERS: CASE REPORT
Vakhtang Khelashvili, Tengiz Shiryaev, Omar Gogia.
Jo Ann University Hospital, Tbilisi, Georgia.
European University, Tbilisi, Georgia.
104-116

PHAGE-BACTERIA INTERACTIONS UNDER METAL STRESS: A STUDY OF THE NOVEL STENOTROPHOMONAS MALTOPHILIA PHAGE VB_STM18
Ia Kusradze, Olia Rcheulishvili, Natia Karumidze, Sophio Rigvava, Aleksandre Rcheulishvili, Rusudan Goliadze, Luka Kamashidze, Alikya Chipurupalli, Nunu Metreveli, Marine Goderdzishvili.
Laboratory of General Microbiology, George Eliava Institute of Bacteriophages, Microbiology and Virology, Tbilisi, Georgia.
Ilia State University, Tbilisi Georgia.
Ivane Javakhishvili Tbilisi State University, Andronikashvili Institute of Physics, Tbilisi, Georgia.
European University, Tbilisi, Georgia.
Caucasus International University, Faculty of Medicine, Tbilisi, Georgia.
117-122

PATHOMORPHOLOGICAL AND CLINICAL CHARACTERISTICS OF THE UTERUS IN COMBINED ADENOMYOSIS AND MYOMA
M.E. Azizova.
Azerbaijan Medical University, Department of Obstetrics and Gynecology II, Baku.
123-127

STUDY OF ORAL HEALTH AND SUPPORTIVE STRUCTURES FOR PROSTHETIC RESTORATIONS IN METHADONE MAINTENANCE THERAPY BENEFICIARIES AND DRUG USERS
Grigoli Dzodzuashvili, Nino Chichua, Vladimer Margvelashvili, Giuli Margishvili, Natia Dzodzuashvili.
Faculty of Medicine, Ivane Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Center for Mental Health and Prevention of Addiction, Georgia.
Dzodzuashvili Dental Clinic, Georgia.
128-133

THE EFFECT OF VITAMIN D ON THE HISTOLOGICAL STRUCTURE OF LIVER AND LUNG IN MICE TREATED WITH AMPHOTERICIN B
Noori Taha Alkhafaji, Mareb H. Ahmed, Bashar Rasim Karem.
Department of Basic Nursing Sciences, Faculty of Nursing, University of Telafer, Nineveh, Iraq.
Department of Dentistry, University of Al-Noor, Nineveh, Iraq.
Department of Biology, College of Education for Pure Science, University of Mosul, Ninevah, Iraq.
134-141

ASSESSING THE KNOWLEDGE LEVEL AND ATTITUDE TOWARDS PROVIDING NUTRITION CARE OF MEDICAL STUDENTS IN THE AKMOLA REGION OF THE REPUBLIC OF KAZAKHSTAN
Muratbekova Svetlana, Beth L. Leonberg, Kulbayeva Shynar, Duisenbina Zhanbota, Lissitsyn Yuriy.
Kokshetau University named after Sh. Ualikhanov, Kokshetau, Kazakhstan.
College of Nursing and Health Professions, Drexel University, Philadelphia, USA.
142-147

IMPROVEMENT OF SURGICAL TREATMENT OF ACUTE BILIARY PANCREATITIS
Aldiyar E. Masalov, Meirbek Zh. Aimagambetov, Medet A. Auyenov, Samatbek T. Abdrakhmanov, Nazarbek B. Omarov, Altay A. Dyusupov, Tolkyn A. Bulegenov, Askar Zh. Akhmetov.
Department of Hospital Surgery, Anesthesiology and Reanimatology NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical
University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
Chairman of the Board Rector NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock
Company), Republic of Kazakhstan.
State Higher Medical College named after D. Kalmataev, Semey, Republic of Kazakhstan.
148-155

A MODERN VIEW ON THE TREATMENT OF CLASS IV RECESSION ACCORDING TO MILLER
Khabadze Z.S, Inozemtseva K.S, Bakaev Yu.A, Magomedov O.I, Kakabadze E.M, Badalov F.V, Saeidyan S, Umarov A.Yu, Wehbe A.
Department of Operative Dentistry, Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Institute of Medicine, Miklukho-Maklaya str. 6, Moscow 117198, Russia
156-162

CORRELATION BETWEEN EJECTION FRACTION (EF) AND CORONARY SINUS BLOOD FLOW (CSBF) DURING OFF-PUMP CORONARY ARTERY BYPASS GRAFTING SURGERY
Christina Ejibishvili, Merab Kiladze, Ioseb Begashvili, George Grigolia.
Tbilisi 5th Clinical Hospital, Javakhishvili Tbilisi State University, Tbilisi, Georgia.
Iv.Javakhishvili Tbilisi State University, American Hospital Tbilisi, Georgia
163-166

MULTIPLE MUSHROOM-LIKE GROWING CYLINDROMAS OF THE SCALP (TURBAN TUMOR) IN A PATIENT WITH BROOKESPIEGLER SYNDROME: UNIQUE MANIFESTATION IN A BULGARIAN PATIENT
Tchernev G, Broshtilova V, Kordeva S.
Onkoderma- Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606 Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Institute of Ministry of Interior, General Skobelev 79, 1606, Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Military Academy, Sofia, Bulgaria.
167-170

BENNETT’S FRACTURE: A NARRATIVE REVIEW OF CURRENT LITERATURE
Arnab Sain, Jack Song Chia, Nauman Manzoor, Minaal Ahmed Malik, Nadine Khayyat, Hamdoon Asim, Ahmed Elkilany, Otto Russell, Venera Derguti, Michele Halasa, Anushka Jindal, Fahad Hussain, Kanishka Wattage, Hoosai Manyar, Justin Wilson, Lulu Chamayi, Hannah Burton, Ansab Mahmood, Wilam Ivanga Alfred, Vivek Deshmukh, Abhinandan Kotian, Zain Sohail.
Worthing Hospital, University Hospitals Sussex NHS Foundation Trust, United Kingdom.
171-173

EARLY PREDICTORS OF NON-UNION OF DIAPHYSEAL TIBIAL FRACTURES BASED ON SCORING SYSTEMS
F. Kh. Umarov, J. J. Samatov.
State Institution "Republican Specialized Scientific and Practical Medical Center for Traumatology and Orthopedics of the Ministry of Health
of the Republic of Uzbekistan", Tashkent, Republic of Uzbekistan.
Samarkand branch of the State Institution "Republican Specialized Scientific and Practical Medical Center for Traumatology and Orthopedics
of the Ministry of Health of the Republic of Uzbekistan", Samarkand, Republic of Uzbekistan.
174-183

DEEP LEARNING-BASED FRAMEWORK TO DETERMINE THE DEGREE OF COVID-19 INFECTIONS FROM CHEST X-RAY
Satyanarayana Kummari, Aniket Madhukar Zope, Prachi Juyal, Pratibha Sharma, Sidhant Das, Sharin Koshy Varghese.
Assistant Professor, Department of Radiodiagnosis, All India Institute of Medical Sciences (AIIMS), Nagpur, Maharashtra, India.
Assistant Professor, Department of Radiodiagnosis, Symbiosis Medical College for Women & Symbiosis University Hospital and Research
Centre, Pune, India.
Assistant Professor, Allied Sciences (Mathematics), Graphic Era Deemed to be University, India.
Centre of Research Impact and Outcome, Chitkara University, Rajpura- 140417, Punjab, India.
Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh-174103 India.
Clinical Nurse Specialist, Heart Hospital, Hamad Medical Corporation, Doha, Qatar.
184-187

BINOCULAR INTERACTION IN AMBLYOPIA
Maghlakelidze Natalia, Zueva Marina V, Petriashvili Giorgi, Skliarenko Sofio.
European University, Tbilisi, Georgia.
Aversi Clinic, Tbilisi, Georgia.
Georgian-American University, Tbilisi, Georgia.
Department of Clinical Physiology of Vision, Federal State Budgetary Institution “Moscow Helmholtz Research Institute of Eye Diseases".
University of Georgia, Tbilisi, Georgia.
188-191

STRATEGIC QUALITY MANAGEMENT OF PROCESSES IN NURSING SERVICES WITHIN INTERNAL AND GENERAL MEDICINE UNITS FOR A SUSTAINABLE FUTURE IN HEALTH SYSTEMS
Mariela Gaibor–González, Diego Bonilla–Jurado, Ember Zumba–Novay, Cesar Guevara.
Ph.D. in Pedagogical Sciences, Faculty of Health and Human Sciences, Universidad Estatal de Bolívar, Guaranda, Ecuador.
Ph.D. in Business Administration, Center for Innovation and Technology Transfer, Instituto Superior Tecnológico España, Ambato 180103, Ecuador.
Master’s in industrial design and Processes, Faculty of Mechanics, Escuela Superior Politécnica de Chimborazo, Riobamba, Ecuador.
Ph.D. in Computer Engineering, Research Center for Mechatronics and Interactive Systems (MIST), Faculty of Education Sciences,
Universidad Tecnológica Indoamérica, Quito, Ecuador.
192-200

INTEGRATED MANAGEMENT OF OVARIAN ENDOMETRIOMAS: PRE- AND POST-SURGICAL USE OF DIENOGEST
Nugesha Grigalashvili, Lali Pkhaladze, Archil Khomasuridze.
Medicine doctorate student at the I. Javakhishvili State University, gynecologist at the New Hospitals, 12 Krtsanisi str., 0114, Tbilisi, Georgia.
Associate Professor, Department of Reproductology and Obstetrics and Gynecology at the Javakhishvili Tbilisi State University, Prof.
Zhordania and Prof. Khomasuridze Institute of Reproductology, 13 Tevdore Mghvdeli str., 0112, Tbilisi, Georgia.
Full Professor, Head of the Department of Reproductology and Obstetrics and Gynecology at the Javakhishvili Tbilisi State University, General
Director of Prof. Zhordania and Prof. Khomasuridze Institute of Reproductology, 13 Tevdore Mghvdeli str., 0112, Tbilisi, Georgia.
201-205

SMALL BUT MIGHTY: CHARACTERIZATION OF VB_SPY_7, A LYTIC PHAGE TARGETING STREPTOCOCCUS PYOGENES
S. Rigvava, I Kusradze, N. Karumidze, M. Chichashvili, I. Tchgkonia, M. Goderdzishvili.
G. Eliava Institute of Bacteriophage, Microbiology and Virology, Tbilisi, Georgia.
Caucasus International University, Tbilisi, Georgia.
European University, Tbilisi, Georgia.
Tbilisi State University, Tbilisi, Georgia.
206-210

ANATOMY OF THE MAXILLARY SINUS: IMPLICATIONS FOR ODONTOGENIC SINUSITIS DEVELOPMENT
Gorbik E.V, Ohurtsov O.S, Heranin S.I, Kolba O.O, Breslavets N.M, Sazonova O.M, Kysylenko K.V, Alekseeva V.V.
Sumy State University, Ukraine.
V.N. Karazin Kharkiv National University, Ukraine.
Kharkiv National Medical University, Ukraine.
Kharkiv International Medical University, Ukraine.
211-216

CARVEDILOL IN PATIENTS WITH UNCONTROLLED AND RESISTANT ARTERIAL HYPERTENSION
Zviad Kereselidze, Lela Kopaleishvili, Kakha Nadaraia, Kakhaber Chelidze, Vakhtang Chumburize.
Department of ICCU, Tbilisi Heart Center, Tbilisi, Georgia.
Department of Cardiology, Chapidze Heart Center, Tbilisi, Georgia.
Department of Clinical and Interventional Cardiology and Therapy, TSU University Hospital Vivamedi, Tbilisi, Georgia.
Department of Internal Medicine, TSMU & Ingorokva High Medical Technologies University Clinic, Tbilisi, Georgia.
217-224

STUDY OF ORBITAL NEOPLASMS BY MAGNETIC RESONANCE IMAGING PROCEDURE
Mirian Getsadze, Sofia Chedia.
PhD student, D. Agmashenebeli University of Georgia, Tbilisi, Georgia.
Tbilisi State Medical University, Clinical Professor, Tbilisi, Georgia.
225-233