CURRENT ISSUE

NOVEMBER 2024

VOL. 356 No. 11

PERSPECTIVE





PROGNOSTIC SIGNIFICANCE OF SST2 IN HEART FAILURE WITH REDUCED EJECTION FRACTION, A BIOMARKER OF CARDIOVASCULAR MORTALITY AND REHOSPITALIZATION
Tamar Shengelia, Bezhan Tsinamdzgvrishvili, Kakha Nadaraia, Liluashvili Konstantine, Talakvadze Tamar.
Ivane Javakhishvili Tbilisi State University, Georgia.
Department of Clinical and Interventional Cardiology and Therapy, Tbilisi State University Clinic Vivamedi, Georgia.
University of Georgia, School of Science, Georgia.
Department of General Internal Medicine, Tbilisi State Medical University, Georgia.
David Tvildiani Medical University, Georgia.
6-12

BIOLOGICAL TREATMENTS AND CARDIOVASCULAR CHANGES IN THE GEORGIAN PATIENT WITH RHEUMATOIDARTHRITIS
N. Tavberidze, N. Sharashidze, T. Bochorishvili.
Ivane Javakhishvili Tbilisi State University, Georgia.
13-17

APPLICATION OF ULTRASOUND TECHNOLOGY IN THE PROCESSING OF HISTOLOGICAL MATERIAL
G. Burkadze, N. Kikalishvili, T. Muzashvili.
Levan Samkharauli National Forensics Bureau, Tbilisi, Georgia.
18-21

SHORT TERM COMPARISON OF CLINIC RADIOGRAPHIC RESULTS OF TOTAL HIP REPLACEMENT WITH SHORT FEMORAL STEM IN OBESE AND NON-OBESE YOUNG PATIENTS. SINGLE CENTER PROSPECTIVE PILOT STUDY
Daniel Godoy-Monzon, Patricio Telesca, Jose Manuel Pascual Espinosa.
Servicio de Ortopedia y Traumatología, Hospital de San Rafael, Hospitales Pascual, Cadiz, España
22-27

IMPROVEMENT OF LOWER LIMB AMPUTATION PROCEDURE IN PATIENTS WITH CRITICAL LOWER LIMB ISCHAEMIA
Zhassulan O. Kozhakhmetov, Ersin T. Sabitov, Yerlan A. Salmenbaev, Merey N. Imanbaev, Tolegen A. Toleutayev, Yernur M, Kazymov, Aldiyar E. Masalov.
Department of Hybrid and Vascular Surgery University Hospital of the NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company).
Director of Emergency Medical Care Hospital, Semey, Republic of Kazakhstan.
Head of the Department of Cardiac Surgery University Hospital of the NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company).
Department of Cardiovascular and Thoracic Surgery named after B.S. Bulanov, NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company).
Department of Cardiac Surgery University Hospital of the NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company).
Department of Hospital Surgery, Anesthesiology and Reanimatology NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
28-38

A CASE REPORT OF DISCONTINUED SPLENOGONADAL FUSION MASQUERADED AS PARATESTICULAR TUMOR
Badr Alharbi.
Department of Surgery, College of Medicine, Qassim University, Buraydah, Saudi Arabia
39-41

STRATEGIES FOR IMPROVING PSYCHOLOGICAL COMPETENCE IN PHYSICAL REHABILITATION
Vitalii Baltian, Elina Manzhalii (Christian), Lesia Volnova, Yuriy Rohalya, Borysova Olesia.
Teacher, Department of Physical Therapy, Occupational Therapy and Physical Education, Faculty of Humanities, Ukrainian Institute of Arts and Sciences, Bucha, Ukraine.
Doctor of Medicine, Associate Professor of the Department of Propedeutics of Internal Medicine No. 2, Bogomolets National Medical University, Kyiv, Ukraine.
PhD in Social Pedagogy, Associate Professor, Associate Professor of Department of Psychosomatics and Health Psychology, Faculty of Psychology, Mykhailo Dragomanov State University of Ukraine, Kyiv, Ukraine.
Senior Teacher, Department of Physical Therapy, Occupational Therapy and Health, Faculty of Human Health and Natural Sciences, Drohobych Ivan Franko State Pedagogical University, Drohobych, Ukraine.
Doctor of Law, Senior Lecturer, Department of General and Differential Psychology, State Institution “Southern Ukrainian National Pedagogical University named after K. D. Ushinsky”, Odesa, Ukraine.
42-49

THE RATIO OF EXCITATORY AND INHIBITORY SYNAPTIC PROCESSES IN NEURONS OF THE ЕNTORHINAL CORTEX OF THE BRAIN, ACTIVATED BY BASOLATERAL AMYGDALA ON THE MODEL OF PARKINSON’S DISEASE, UNDER CONDITIONS OF PROTECTION BY HYDROCORTISONE
Varduhi Suren Hovsepyan, Gohar Mkrtich Arajyan, Abdulwahabb Al-Chachani, Gohar Khristafor Musheghyan, John Sarkissian, Ivan Georgi Gabrielyan.
Eurasia International University, Azatutyan 24/2, 0014, Yerevan, Armenia.
Institute of Botany after A. Takhtajyan NAS RA, 1 Acharyan St., 0063, Yerevan, Armenia.
Armenian State Pedagogical University after KH. Abovyan, 17 Tigran Mets str. Yerevan, Armenia.
Scientific Technological Center of Organic and Pharmaceutical Chemistry NAS RA, 26 Azatutyan Ave, 0014, Yerevan, Armenia.
Orbeli Institute of Physiology NAS RA, 22 Orbeli Bros Street, 0028, Yerevan, Armenia.
50-58

ANTIMICROBIAL ACTION OF A MODIFIED UNIVERSAL ADHESIVE: AN IN VITRO STUDY
Hisham I. Wali, Sawsan H. Al-Jubori.
Conservative Dentistry Department, Dentistry faculty, Tishk International University, Erbil, Iraq.
Department of Conservative Dentistry, College of Dentistry, University of Mosul, Mosul, Iraq.
59-65

SATISFACTION WITH THE QUALITY AND AVAILABILITY OF MEDICAL SERVICES IN RURAL AREAS OF KAZAKHSTAN
Assiya Turgambaeva, Ainagul Tulegenova, Serik Ibraev, Stukas Rimantas, Aigerim Alzhanova, Dinara Ospanova, Maiya Toleugali.
Professor, Head of the Department of Public Health and Management, NJSC "Astana Medical University", Astana, Kazakhstan.
Doctoral candidate of the Department of Public Health and Management, NJSC "Astana Medical University", Astana, Kazakhstan.
Doctor of medical sciences, professor of the Department of Public Health and Management, NJSC "Astana Medical University", Astana, Kazakhstan.
Professor, dr. (HP), Institute of Public health faculty of Medicine of Vilnius university, Lithuania, Vilnius.
Senior Lecturer of the Department of Public Health and Management, NJSC "Astana Medical University", Astana, Kazakhstan.
Head of the Department of Nursing of the Higher School of Medicine of the Faculty of Medicine and Health Care, Al-Farabi Kazakh National  University, Almaty, Kazakhstan.
Lecturer at the Department of Nursing of the Faculty of Medicine and Public Health of the Kazakh National Medical University named after S.D. Asfendiyarov, Almaty, Kazakhstan.
66-73

ORAL MANIFESTATIONS IN JUVENILE SCLERODERMA: CLINICAL PRESENTATIONS AND HISTOPATHOLOGICAL CHARACTERISTICS
Skakodub A.A, Osminina M.K, Geppe N.A, Admakin O.I, Kozlitina Y.A, Goryaynova A.V.
Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Russia.
74-81

PROGRESSES IN PERSONALIZED NURSING ON THE PERIOPERATIVE PERIOD OF HEPATOBILIARY
Jing Liu.
Department of general surgery. Jiaozhou Central Hospital of Qingdao, Jiaozhou 266300, Qingdao, Shandong, China.
82-83

INCUOLATION THE BOTULINUM TOXIN-B IN THE ZYGOMITICUS OF THE RAT, FOLLOWED BY EVALUATION IT’S EFFECT HISTOLOGICALLY ON THE ZYGOMATIC BONE
Ali K. Obeys, Huda A. Hameed, Ali I. Mohammed Salih.
Department of biology, College of Education for Women, University of Kirkuk, Kirkuk, Iraq.
Department of Pharmacology, Physiology and Biochemistry, College of Veterinary Medicine, University of Tikrit, Tikrit, Iraq.
84-88

POLYPHARMACY AND CANCER: А NEW VISION FOR SKIN CANCER PATHOGENESISPHOTOTOXICITY AND PHOTOCARCINOGENICITY DUE TO NITROSAMINE CONTAMINATION DURING TELMISARTAN/ TAMSULOSIN INTAKE
Tchernev G, Kordeva S, Kirilova H, Broshtilova V, Patterson JW.
Onkoderma- Clinic for Dermatology, Venereology and Dermatologic Surgery, General Skobelev 26, 1606 Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Institute of Ministry of Interior, General Skobelev 79, 1606, Sofia, Bulgaria.
Department of Dermatology and Venereology, Medical Military Academy, Sofia, Bulgaria.
Professor Emeritus of Pathology, Department of Pathology, University of Virginia, Charlottesville, USA.
89-93

INTRAORAL SCANNERS AND CONVENTIONAL IMPRESSIONS: A LITERATURE REVIEW
Gem Muçolli, Fidan Nikç, Genit Muçolli.
Private dental Clinic “Ismile Dental Studio”, Prishtina, Republic of Kosovo.
Private dental Clinic “Vurall Dent” Peja, Republic of Kosovo.
94-99

EVALUATION OF VITAMIN D LEVEL IN SERUM OF PATIENTS WITH VITILIGO
Farah Saleh Abdul-Reda, Mohammed AH Jabarah AL-Zobaidy.
Assistant professor (PhD) in Dermatology, Department of Medicine, College of Medicine, University of AL-Qadisiyah, AL-Diwaniyah, Iraq.
Assistant professor (PhD) in Pharmacology, Department of Pharmacology, College of Medicine, University of Baghdad, Baghdad, Iraq.
100-102

APPLICATION OF EARLY RISK FACTOR WARNING MODEL OF ACUTE KIDNEY INJURY COMBINED WITH CONTINUOUS RENAL REPLACEMENT THERAPY IN PATIENTS WITH SEVERE ACUTE PANCREATITIS
Li-Juan Ru, Qian-Qian Yao, Ming Li.
Department of Critical Care Medicine, Jiaozhou Central Hospital of Qingdao, Jiaozhou 266300,Shandong,China
Department of Ophthalmology, Jiaozhou Central Hospital of Qingdao, Jiaozhou 266300, Shandong, China.
103-106

PREVALENCE AND DISTRIBUTION OF ODONTOGENIC CYSTS: A 12-YEAR RETROSPECTIVE STUDY
Mammadov F.Y, Safarov M.A, Mammadov K.J, Alkishiev K.S.
Faculty of Dentistry, Azerbaijan Medical University, Baku, Azerbaijan.
Clinic of Maxillofacial and Facial Surgery, Ludwig Maximilian University, Munich, Germany.
107-111

TRIPLE THERAPY COMBINED WITH ACCELERATED RECOVERY STRATEGY CAN IMPROVE THE QUALITY OF LIFE OF ELDERLY PATIENTS WITH MECHANICAL VENTILATION
Qiu-Lin Chen, Nie-Hong Zou, Ming-Li Zhu.
Department of Nursing, Hangzhou Geriatric Hospital, Gongshu District,310022 Hangzhou, Zhejiang, China.
Department of Out-patient, Hangzhou Geriatric Hospital, Gongshu District, 310022 Hangzhou, Zhejiang, China.
112-117

IMPORTANCE AND URGENCY OF TREATMENT AND PREVENTION STRATEGIES OF COMPLICATIONS IN ORTHODONTIC PATIENTS - LITERATURE REVIEW
Maria Nikuradze, Zurab Artmeladze, Ann Margvelashvili, Vladimer Margvelashvili, Manana Kalandadze.
Tbilisi State University, Chavchavadze ave. 1, 0179, Tbilisi, Georgia.
Georgian National Museum, Purtseladze str. 3, 0105, Tbilisi, Georgia.
The University of Georgia, Kostava str. 77a, 0171, Tbilisi, Georgia.
118-123

CLINICAL AND LABORATORY PREDICTORS OF ADVERSE OUTCOME WITH SEVERE COVID-19 IN COMORBID PATIENTS OF THE KARAGANDA REGION (REPUBLIC OF KAZAKHSTAN
Yevgeniya Li, Yerzhan Zhunussov, Bakhyt Kosherova, Gheorghe Placinta, Bibigul Tulegenova.
Department of Infectious Diseases and Phthisiology, Karaganda Medical University, Karaganda, Republic of Kazakhstan.
Department of Pediatric Infectious Diseases, Astana Medical University, Astana, Republic of Kazakhstan.
Department of Infectious Diseases, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.
Health Administration of the Karaganda Region, Karaganda, Republic of Kazakhstan.
124-129

REGENERATIVE MATERIALS-THEIR INDICATIONS AND USE IN IMPLANTOLOGY: A LITERATURE REVIEW
Fidan Nikç, Gem Muçolli, Genit Muçolli.
Private dental Clinic “Vurall Dent” Peja, Republic of Kosovo.
Private dental Clinic “Ismile Dental Studio”, Prishtina, Republic of Kosovo.
130-135

HYDROGEN SULFIDE AND CYSTATHIONINE Γ –LYASE LEVELS FOR PATIENTS WITH PARKINSON’S DISEASE
Kinda M. Al-Taee, Luay A. Al-Helaly.
Department of Chemistry, College of Education for Pure Science, University of Mosul, Mosul, Iraq.
Department of Chemistry, College of Science, University of Mosul, Mosul, Iraq.
136-140

CLINICAL EFFICACY OF DIFFERENT SURGICAL METHODS IN CONGENITAL PREAURICULAR FISTULA SURGERY
Hui-Xiu Luo, Shu Zhu, Jing-Chuan Wang.
Department of Otolaryngology, Jiaozhou Central Hospital of Qingdao, Qingdao,266603 Shandong, China.
141-143

LONG-LASTING EFFECTS OF EARLY POSTNATAL DYSFUNCTION OF THE BRAIN MUSCARINIC CHOLINERGIC SYSTEM ON LEARNING AND MEMORY AND ADULT HIPPOCAMPAL NEUROGENESIS
Melano Shavgulidze, Neli Maglakelidze, Nino Rogava, Khatuna Bezhanishvili, Nargiz Nachkebia.
Lab. Neurobiology of Sleep-Wakefulness Cycle, Ivane Beritashvili Center of Experimental Biomedicine, Tbilisi, Georgia
144-151

ORAL HEALTH OF CHILDREN IN MY COUNTRY
Jon Kotori, Rrezarta Muqa, Merita Kotori.
Department of Dentistry, Alma Mater Europaea Campus College Rezonanca, Prishtina, Kosovo.
Department of Dermatology, Alma Mater Europaea Campus College Rezonanca, Prishtina, Kosovo.
152-155

BIBR1591 INDUCES APOPTOSIS IN BREAST CANCER CELL LINE AND INCREASES EXPRESSION OF DAPK1, AND NR4A3
Zahraa Alsarraf, Ali Yousif Nori, Amjad Ibrahim Oraibi, Hany Akeel Al_hussaniy, Alhasan Ali Jabbar.
Department of Pharmaceutical Chemistry, College of Pharmacy, Nineveh University, Nineveh, Iraq.
Department of Pharmacy, AL Mustafa University College, Baghdad, Iraq.
AL-Manara College for Medical Science, Pharmacy Department, Amarah, Iraq.
Department of Pharmacy, Al-Nisour University College, Baghdad, Iraq.
Dr Hany Akeel Institute, Iraqi Medical Research Center, Baghdad, Iraq.
156-160

VIRTUAL ENVIRONMENTS AND HUMAN ANATOMY LEARNING ACHIEVEMENTS IN UNIVERSITY STUDENTS
María Jackeline Cuellar Florencio, Marcos Julio Saavedra Muñoz, Yuri Anselmo Maita Cruz, Santa Dolores Torres Álvarez, María Ysabel Casanova Rubio, Eduardo Frank Loli Prudencio, Walter Gomez-Gonzales.
Facultad de Medicina, Departamento Académico de Enfermería, Universidad Nacional Mayor de San Marcos. Lima-Perú.
Facultad de Medicina, Departamento de Medicina Preventiva Y Salud Publica, Universidad Nacional Mayor de San Marcos. Lima-Perú.
Facultad de Medicina, Departamento Académico de Ciencias Morfológicas, Universidad Nacional Mayor de San Marcos. Lima-Perú.
Escuela de Medicina Humana. Universidad Privada San Juan Bautista. Ica, Perú.
161-164

COST-EFFECTIVENESS OF TREATMENT OF RHEUMATOID ARTHRITIS WITH BIOLOGICAL DRUGS IN GEORGIA
S. Shalamberidze, N. Chikhladze.
Ivane Javakhishvili Tbilisi State University, Georgia.
165-170

APPLICATION OF IMPROVED AUTODERMOPLASTY TECHNIQUE IN GRANULATING WOUNDS TREATMENT
Nursultan K. Andasbekov, Nazarbek B. Omarov, Sagit B. Imangazinov, Yernar K. Kairkhanov, Olga G. Tashtemirova, Rustem S. Kazangapov, Saule S. Imangazinova, Aldiyar E. Masalov.
Department of Hospital Surgery, Anesthesiology and Reanimatology NCJSC «SMU», Semey, Republic of Kazakhstan (Semey Medical University, Non-Commercial Joint-Stock Company), Republic of Kazakhstan.
Department of Surgery, Pavlodar branch of NCJSC "SMU", Semey, Republic of Kazakhstan (Medical University of Semey, Non-profit jointstock company), Republic of Kazakhstan.
Director of Pavlodar branch of NCJSC "SMU", Pavlodar, Republic of Kazakhstan (Medical University of Semey, Non-profit joint-stock company).
Dean of the Pavlodar branch of NCJSC "SMU", Pavlodar, Republic of Kazakhstan (Medical University of Semey, Non-profit joint-stock company).
Head of the Department of Surgery of the Pavlodar branch of NCJSC "SMU", Pavlodar, Republic of Kazakhstan (Medical University of Semey, Non-profit joint-stock company).
Department of Internal Medicine of NCJSC «AMU», Astana, Republic of Kazakhstan (Astana Medical University, Non-Commercial Joint-Stock Company).
171-175

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