USE OF OPTICAL COHERENCE TOMOGRAPHY IN DETECTION OF CYSTOID MACULAR EDEMA AFTER TREATMENT WITH NONSTEROIDAL ANTI-INFLAM- MATORY DRUGS
Dvali M., Tsertsvadze O., Skhirtladze Sh.
Tbilisi State Medical University, Department of Eye Desease;
Eye clinic “Akhali Mzera”, Tbilisi, Georgia
The aim of the study was to determine the correlation between implanted IOL material type to detect CME after NSAID use in cataract surgery. Study involved 94 eyes of 72 patients. Eyes were equally divided into two groups (n-47 in each). Post-operatively treatment regimen for participants from Group I included antibiotic and NSAID eye drops, while participants from group II were treated only with antibiotic eye drops. Acrylic hydrophobic intraocular lens (IOL) was implanted in all patients comprising both groups. No patient developed cystoid macular edema from either group (CME). In both groups (with or without NSAID eye drops cover) mean central retinal thickness (CRT) was 230±0.005 microns before the surgery. No statisti- cally signi cant changes of CRT was noted in both groups (5± 0.09 microns ) (p<0.5).
Study analysis has shown, that cystoid macular edema has not developed in patients, who underwent uncomplicated cataract surgery with hydrophobic IOL implantation, with or without NSAID eye drop cover. There was no statistically and clinically significant difference between the groups in terms of CRT.
Implantation of acrylic hydrophobic intraocular lens (IOL) has shown to provide high uveal biocompatibility.
Major risk factors of CME in cataract surgery are intra-operative surgical complications. Certain systemic and local ophthalmic diseases, as well as topical use of prostaglandin analogs are also strongly linked to postoperative CME development.
In conclusion, usage of NSAID eye drops in combination with antibiotic regimen in eyes undergoing cataract surgery, showed to have a bene cial e ect on prevention of postoperative CME.
Cystoid Macular Edema
Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Intraocular Lens (IOL)